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So welcome back. We are on the third and hopefully final, rendition of Save the Mullet. So, we’re talking about, of course, the science and of course the treatment for hair restoration. And we’re at the … probably the most important kind of pinnacle of the whole podcast. And we’re talking about the really interesting and, you know, most cutting edge treatments of you know, this type of, you know, medicine right now, that we’re gonna get to. So it was worth the wait, don’t you think so?

I totally promise, guys, it’s 100% worth the wait. You guys have learned a lot about the history and the science behind hair loss. So now we’re really gonna get into the solutions.

Yeah. I mean, last time we did talk about some of the, you know, more common treatments. We talked about you know, Minoxidil, we talked about some of the other treatments, Finasteride. We also talked about the low laser light therapy, which has really some pretty good research on it as well. So now we’re gonna talk about Platelet Rich Plasma, which … has really good data and it is one of the new cutting-edge treatments. It’s been out for a good period of time. And we’re gonna talk a little bit about it, and we’re gonna talk about the efficacy, and we’re gonna talk about the science behind it.

And we’re gonna talk about why I think that this is gonna be one of the important treatments that we’re gonna discuss. … We talked a little bit about it before on one of the other podcasts, specifically about skin treatments. But, you know, let’s get into, you know, what the data is behind Platelet Rich Plasma with hair treatments because I think that there’s pretty good data when it comes to hair and Platelet Rich Plasma.

PRP is … we’ve seen a really amazing results at the office.

Yeah, Platelet Rich Plasma. So when you think about with platelet rich plasma, whenever you cut yourself, for instance … what happens is that you have certain cells that come to you. And those cells … one of the most, you know, important cells are platelets. The platelets are those wound-healing cells. They are the cells that come and they’re kind of the first responders. They’re the ones that are there for you that come to kind of help to … just, you know, get the important growth factors to kind of heal the wound, help to get … lay down the tissue that’s gonna be important to help the, you know … new skin, you know, that’s gonna be there … present. So platelets are super important when you have some type of wound present. So that’s the way I kind of think of a Platelet. So … that’s why I think platelets are really important, you know, when it comes to this type of medicine.

I like that you call them the first responders. Let’s see … that really nails it.

Yeah, I mean, I think that they … that kind of gives the … it gives the kind of good … visualization of what, like … platelets are. And so that’s the reason why platelets have been kind of to the forefront of all this type of medicine. Now, platelets have been used in orthopedic medicine very successfully. You know, when you think about the fact that, you know, athletes have been you know, damaging and tearing ligaments and they’ve been putting platelets into their joints … and repairing ligaments with platelets. You think about how significant that is … of the wear and tear of a ligament that platelets can actually repair a ligament. What it could do to delicate tissue like skin and hair. You know, that it … it’s pretty impressive that … it could repair a ligament that you think that it could do some, you know, good things with skin and hair as well. I mean, when you really think about those factors.

So here are the high points when you think about what platelet, you know, like what platelet plasma is gonna do. So the first thing is Angiogenesis a big word means that it brings blood to the area. Is that a good thing?

Sounds like it.

Yeah, of course, because what it does is, it’s gonna bring all the nutrients, like blood is kind of like the, you know … like is the supermarket of the you know … of the skin. So, and of course, in this case to the follicles and of the scalp. So it kind of gives all the nutrients it brings, the oxygen, it gives you … it nourishes, you know, the areas that, you know, were dormant and kind of waiting for, you know, that area to be kind of refilled. So when you have, you know, that dormant kind of cells that are sitting there waiting to go into the, you know, the more growth phase, you need something to kind of precipitate it. So, you know, the first step to … get things moving is … the, you know, the Angiogenesis also reducing inflammation. And I’m gonna talk a little bit about this you know, again.

Inflammation is one of the biggest reasons why … we do go into the phase of hair loss, you know, the catagenic phase where we lose hair. Because of the fact that when we have inflammation in the scalp, and we talked about like when you could produce inflammation by, you know, using traction, by … putting yourself into a ponytails or you know, braids, you know, you cause inflammation into those follicles, you’re gonna be damaging those follicles. But you know, specific inflammation, you know, does damage to the follicles and it could cause you know … the follicles to cause the hair to be … to be lost. So we want anti … inflammatory errors to the scalp.

So, if it’s the area the follicle has been damaged by, you said, like wearing hats a lot or tight scarfs around your head, or like you said, put in a ponytail …

Right.

… … the guy in Pulp Fiction, what’s his name? Why am I blanking? John Travolta …

John Travolta.

… and his pony ponytail…

Right?

… that can cause hair loss.

Right?

So we wanna do … or we wanna reduce inflammation around the follicle.

Exactly. So, and … so that’s really important and it’s an important concept, and we’re gonna talk about that a little bit later when we get into the final conclusions to the podcast. And then also one of the important things that the PRP does is it stimulates the … Follicle Papillae, remember we talked about, this is the trigger